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Topical Platelet-Derived Growth Factor vs Placebo Therapy of Diabetic Foot Ulcers Offloaded With Windowed Casts: A Randomized, Controlled Trial

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  Abstract: Objective. This study sought to compare the efficacy of topical platelet derived growth factor (Regranex, Smith and Nephew, London, UK) (test group) to placebo (control group) in treating diabetic foot ulcers. All subjects had a short leg walking cast with a window fashioned in the cast over the site of the ulcer....

SCALE Wounds: Unavoidable Pressure Injury

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  Abstract: Skin Changes at Life’s End (SCALE) wounds include wounds of many underlying etiologies that accompany the dying process. These wounds occur due to unmodifiable intrinsic and extrinsic factors unique to each individual. This article describes the case of a dying patient who sustained a skin tear that deteriorated into a SCALE wound that meets the criteria for a National Pressure Ulcer Advisory Panel unavoidable pressure injury....

Degree of the Hazards of Silver-Containing Dressings on MRSA-Infected Wounds in Sprague-Dawley and Streptozotocin-Induced Diabetic Rats

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  Abstract: Silver-containing dressings are commonly used on healing wounds, including diabetic ulcers. Some studies have shown that dressing materials with silver have negative effects on wound healing, specifically, that the wound healing process is inhibited by deposited silver. Therefore, the authors treated wounds infected with methicillin-resistant Staphylococcus aureus (MRSA) in Sprague-Dawley (SD) rats and streptozotocin (STZ)-induced diabetic rats with silver dressings to evaluate the risks of silver....

The Efficacy and Safety of Natural Honey on the Healing of Foot Ulcers: A Case Series

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  Abstract: This clinical observation investigated the efficacy, cost-effectiveness, and acceptability of natural honey on the healing of a variety of chronic foot ulcers at the primary care level....

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The test method described in this paper allows simple, quantifiable, and visual comparison of the moisture level within the simulated periwound when covered with different types of wound dressings. These findings could aid clinicians in selecting appropriate dressings for wounds with varying levels of exudate.

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