Volume 24 - Issue 8 - August 2012

AAWC News

AAWC and DebRA Join Forces

  The Association for the Advancement of Wound Care (AAWC) and the Dystrophic Epidermolysis Bullosa Research Association of America (DebRA) are working together to bring wound care professionals where they’re needed most — to patients and families living with Epidermolysis Bullosa (EB).

  Frequently, Association members ask about opportunities to help the underserved in this country. This partnership will provide AAWC members a way to volunteer to help improve the quality of care for EB sufferers and their families. Join AAWC today to take part in this effort. For more information on volunteering, contact project manager Karen Strauss at kstrauss@aawconline.org.



Evidence Corner: Biologic Dressings for Foot Ulcers

Dear Readers:
  Healthy feet help us preserve our independence, earn our livelihood, and participate actively in our social environment. A foot ulcer can isolate and depress the individual who suffers it while increasing risk of amputation, infection, or mortality. Healing foot ulcers quickly helps limit the costs and burden of care and keeps patients active as contributing members of family and society. Most foot ulcers will decrease in area by at least 50% in 4 weeks and proceed to complete healing by 12 weeks1,2 when their growth factor-rich, enzyme-laden fluid is sealed over the wound, cause(s) of injury stopped, and devitalized tissue removed.1



Ultrasound-Mediated Oxygen Delivery to Lower Extremity Wounds

Index: WOUNDS. 2012;24(8):201–206.

  Abstract: Critical limb ischemia (CLI), an end result of peripheral arterial disease, remains a major clinical challenge. Wound healing in patients with CLI can be difficult due to diminished tissue oxygenation, often leading to recalcitrant ulcers and frequent limb loss. Numerous therapies, including hyperbaric oxygen therapy (HBOT), have been used to correct this regional ischemia, although often with mixed results. This case series investigates the effects of oxygen therapy delivery augmented by low-frequency ultrasound, a device that combines surface acoustic waveform (SAW) low-frequency ultrasound with hyper-oxygenated saline to deliver oxygen to wounds. Participants included 7 patients (7 men, median age 63 years, all with hypertension) with CLI and full-thickness wounds. Baseline therapy PaO2 measurements were taken before therapy, after provision of hyper-oxygenated saline, and after sonification. The device was found to successfully oxygenate the wound beds; PaO2 levels increased by a median of 59.7%, a maximum of 116%, and a median absolute difference peaking at 10.8 mmHg PaO2 (P = 0.018). In conclusion, the treatment increases wound oxygen levels and may be an option in CLI therapy.



Letter to the Editor

Dear Editor:

  In June 2012, (WOUNDS. 2012;24(6):152–159), an article I authored regarding the clinical and economic benefits of healing diabetic foot ulcers (DFU) with total contact casts (TCC) was published. Since the time of publication, I have received feedback regarding a couple of points that require clarification.



New Products and Industry News

Advanced Biohealing Changes Name to Shire Regenerative Medicine

  Shire plc (San Diego, CA) announced that Advanced BioHealing, Inc, which was acquired by Shire in 2011 as a wholly-owned subsidiary focused on regenerative medicine, has changed its name to Shire Regenerative Medicine, Inc, effective immediately. The name change follows a recent announcement that the company plans to build a regenerative medicine campus in San Diego to expand its operational footprint and presence in the area over the next several years.

  Shire Regenerative Medicine is focused on developing and delivering solutions that support Dermagraft®, is a bio-engineered skin substitute indicated for use in the treatment of full-thickness diabetic foot ulcers.



Using Physical Modalities in the Treatment of Venous Leg Ulcers: A 14-year Comparative Clinical Study

Index: WOUNDS. 2012;24(8):215–226.

  Abstract: Venous ulcers are prevalent, challenging wounds; their incidence is rising with the increasing age of the general population. Physical modalities often are used to help heal these chronic wounds. A prospective study was conducted to investigate the application of high-voltage stimulation (HVS), ultrasound therapy (US), low-level laser therapy (LLLT, 810 nm, 65 mW, 4 J/cm2), and compression therapy (CT), with and without surgical intervention; along with standard of care comprising drug therapy (micronized flavonoid fraction in two 500-mg tablets once daily) and wet dressings of 0.9% sodium chloride on venous leg ulcer healing. Methods. The 305-patient study was conducted between 1994 and 2008 among persons with venous ulcers in 3 facilities in Poland. After surgery involving crossectomy, partial [short] stripping of the greater or short saphenous vein, local phlebectomy, and ligation of insufficient perforators, 4 groups of patients were treated with the standard of care drug/dressing therapy and HVS, US, LLLT, or CT, and 1 group received the drug/dressing therapy only. Four non-surgical groups received HVS, US, LLLT, or CT and drug/dressing therapy, and 1 group received drug/dressing therapy only.



Why Don’t You Get It?

Dear Readers,
  What is it about learning and using new information we just don’t get? We spend hours and hours accumulating new information to help our patients, yet we rarely practice what we have learned. Before you say, “That’s not true,” consider the issue of wet-to-dry dressings. We have known since 1963 that wounds heal faster, with less pain, and less scarring under moist conditions.1,2,3 Yet, wet-to-dry dressings are still used 5 times more than moisture retentive dressings.4 We have found the international wound care community is also not immune to this “selective memory loss.” During a recent trip to Ghana, Africa, to provide additional wound care training to hospitals where we had previously taught, we found many clinicians treating wounds the same way they had been for years—with wet-to-dry gauze and povidone-iodine soaked gauze. Why don’t we utilize the good information we are taught so our patients can receive the benefit of the best care currently available?



Clinical Experience With the Use of Gauze-based Negative Pressure Wound Therapy

Index: WOUNDS. 2012;24(8):227–233.

  Abstract: Purpose. In this preliminary study, gauze-based negative pressure wound therapy (NPWT) was used to accelerate granulation tissue formation and promote closure in a number of wound types. The authors aimed to evaluate the efficacy of gauze-based NPWT using the Chariker-Jeter technique for wounds requiring delayed closure. Methods. A retrospective review was conducted of 50 patients with wounds not suitable for immediate primary closure. After initial irrigation, debridement, and antibiotic therapy, Chariker-Jeter technique NPWT was used and dressings were changed at 24- to 48-hour intervals before secondary closure or primary closure. In addition, a 4-point category scoring system (severe, moderate, mild, and none) was used to evaluate pain. Semi-quantitative data also were obtained. Results. Wound size decreased considerably, granulation tissue formation was accelerated, and exudate was reduced and removed by the end of the treatment.



Cost Effectiveness of an Air-inflated Static Overlay for Pressure Ulcer Prevention: A Randomized, Controlled Trial

Index: WOUNDS. 2012;24(8):207–214.

  Abstract: Numerous pressure-relieving surfaces of varying costs are available for the prevention of pressure ulcers. There is insufficient evidence to draw conclusions regarding the efficacy or merits of using more expensive technologies. The purpose of this unblinded, randomized, prospective study was to compare the clinical and the cost effectiveness of an inflated overlay with rented, pressure-relieving surfaces for the prevention of pressure ulcers. Methods. Patients in a 257-bed acute care facility were included if they had a Braden score of < 14, had no skin lesion(s), were 18 years, weighed <300 lb, and submitted signed consent. One hundred, ten patients (110) were randomized into a control group using either a microfluid static overlay (MSO) or a low-air-loss dynamic mattress (LALDM) with pulsation (n = 55) or into an experimental group using an inflated static overlay (ISO) (n = 55). Both groups had identical positioning protocols. No statistically significant differences were noted between the 2 groups with regard to age, gender, weight, or Braden scale score.