Volume 15 - Issue 9 - September, 2003
August Letter from the Editor
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Dear Readers:
In the Evidence Corner, Dr. Laura L. Bolton reviews two published studies reporting the efficacy of pulsed-dye laser (PDL), intralesional corticosteroid, intralesional corticosteroid plus 5-fluorouracil (5-FU), or 5-FU alone on ameliorating surgical and burn wound scars. All the treatment approaches were effective. Dr. Bolton states “…that the evidence base for scar therapy is gradually growing stronger.”
Arseculeratne, et al., (A comparison of light reflection rheography and Duplex scanning in the diagnosis of chronic venous insufficiency) conducted a retrospec
Treatment of Scar Tissue
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Dear Readers:
Scar tissue, the natural result of dermal repair, is less organized than the original dermis it replaces. From this physiologic perspective, maintaining skin integrity is better than repairing it. Excessive or prolonged dermal inflammation can result in elevated, thick, or nodular hypertrophic scars. Keloids differ from hypertrophic scars, often being associated with pigmented skin and progressively involving tissue beyond the zone of the original wound. Both hypertrophic scars and keloids are usually considered “too much of a good thing” with the healing process
A Comparison of Light Reflection Rheography and Duplex Scanning in the Diagnosis of Chronic Venous Insufficiency
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This study was presented at the Sixteenth Annual Symposium on Advanced Wound Care and Medical Research Forum on Wound Repair (SAWC), April 28–May 1, 2003, in Las Vegas, Nevada, and was recognized for its excellence in clinical research.
Introduction
Venous ulcers constitute the majority of all leg ulcers.[1] Venous disease accounts for 1 to 2 percent of the healthcare budgets of European countries.[2] Early signs of chronic venous insufficiency (CVI) are varicose veins and acute lipodermatosclerosis.[3] Progressive changes of CVI include brown hyperpigmentation of the skin caused by ex
Experience with Bilaminate Bioartificial Skin Substitute and Ultrathin Skin Grafting in Non-Burn Soft-Tissue Wound Defects
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Presented at the International Society for Burn Injuries (ISBI) 11th Congress, Seattle, Washington, August, 2002.
Introduction
Surgical closure of large soft-tissue wounds presents a surgical problem in the care of patients who develop these defects. These defects predispose the patients to the development of infection and sepsis with subsequent high morbidity and mortality rates. Early excision and grafting have shortened hospital stay and decreased infectious complications in burn patients.[1] As with burns, autografting is necessary for definitive wound closure in patients with large
Efficacy and Safety of Recombinant Human Platelet-Derived Growth Factor-BB (Becaplermin) in Patients with Chronic Venous Ulcers:
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Introduction
The exact prevalence of venous ulcers is unknown, but estimates from the United States suggest that between 600,000 and 2.5 million individuals in the US suffer from these chronic, debilitating wounds,[1] while estimates indicate that between 0.15 percent and 1 percent of the European population suffer from this condition.[2,3] Thus, venous ulceration represents a common problem, particularly in the elderly population.[4]
Venous ulcers are associated with a significant disease burden, as these ulcers are painful, are difficult to heal, and recur frequently. Current treatment
The Application of a Fibroblast Gel Contraction Model to Assess the Cytotoxicity of Topical Antimicrobial Agents
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Disclosure: Financial support for this work was provided by ConvaTec Ltd., United Kingdom.
Introduction
Since the introduction of a fibroblast-populated collagen lattice in the late 1970s, this type of in-vitro model has been extensively used to study fibroblast function.[1,2] Contraction of fibroblast/collagen gels has been used as in-vitro models for investigating the biological mechanisms of wound contraction[3,4] and also the effects of various compounds aimed at stimulating (enhancing wound healing) or reducing (preventing scar formation) the rate of contraction.[5] The benefit of t
Burning Feet due to Diabetic Neuropathy
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CME/CPME ACTIVITY
Department Editor: Tania J. Phillips, MD, FRCPC
Overall Learning Objective: The physician or podiatrist participant will develop a rational approach to the evaluation and treatment of a variety of uncommon wounds and will have an increased awareness of the differential diagnosis of cutaneous wounds and the systemic diseases associated with these wounds.
Submissions: To submit a case for consideration in Diagnostic Dilemmas, e-mail or write to: Executive Editor, WOUNDS, 83 General Warren Blvd., Suite 100, Malvern, PA 19355, eklumpp@hmpcommunicati
August 2003 Product News
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AVHC’s Portable Hyperbaric Chamber Saves Limbs of Diabetic Patients
Advanced Healthcare Technologies, Inc. announces that in two recent cases AVHC’s Topical Hyperbaric Oxygen Extremity Chambers were utilized to treat patients suffering from diabetes who had nonhealing infected wounds on their extremities. Both patients were facing the threat of below-the-knee amputations.
Dr. Frank Rossi, Medical Director of the St. Francis Hospital Wound Care Center in New Jersey and wound care expert, was recently called to consult on a diabetic patient with renal failure who had extensive gangrene
August 2003 Industry News
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Smith & Nephew Launches Bamboo, a New Wound Management Improvement Business
Smith & Nephew Inc., Wound Management Division, a subsidiary of Smith & Nephew plc, announces the formation of Bamboo, a wound management outcomes tracking and improvement business designed to help healthcare providers improve quality and financial performance in their wound care delivery.
Bamboo enables healthcare providers to get better results from their wound management programs. By bringing together clinical, business, and information technology expertise, Bamboo will support improved planning, decision maki
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