Volume 16 - Issue 2 - February, 2004
February 2004
- 2/10/2004
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Dear Readers:
Last December, a symposium was held in San Francisco to honor Dr. Thomas K. Hunt for his contributions in wound healing research. Dr. Hunt, Professor Emeritus at the University of California School of Medicine, has published important papers on many aspects of wound healing and is best known for his work on the effects of oxygen on repair. In addition to his own research, he has trained many fine clinicians and researchers in our field. It is fitting that Dr. Laura Bolton in the Evidence Corner honors Dr. Hunt by devoting her section to papers on the effects of hyperbaric oxyg
Hyperbaric Oxygen
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Dear Readers:
To honor T. K. Hunt, MD, Emeritus Professor of Surgery at the University of California, San Francisco, we devote this Evidence Corner to hyperbaric oxygen (HBO). Professor Hunt has been a mentor to many and a key contributor to the science of wound healing. Among his distinguished works, he and his colleagues discovered how chronic tissue hypoxia stimulates capillary proliferation.[1] As a result of this work, some hypothesized that increasing oxygen gradients by increasing the oxygen supply to tissue surrounding chronic wounds would improve healing, particularly for ischemic
Wet-to-Dry Gauze Dressings: Fact and Fiction
- 2/10/2004
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Introduction
The purpose of this article is to bring to the attention of surgeons some of the literature on wound dressings and the concomitant lack of research base for their practice of utilizing wet-to-dry and gauze dressings. The aims of the research described here were to identify what actually constitutes a wet-to-dry dressing, explain why it is used, and describe how specialist nurses interpret this technique.
Review of Current Literature
Wet-to-dry and gauze dressings are the most widely used primary dressing material in the United States (US),[1] and there is evidence that t
February 2004 Editorial Message
- 2/10/2004
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February 2004
Dear Readers:
Last December, a symposium was held in San Francisco to honor Dr. Thomas K. Hunt for his contributions in wound healing research. Dr. Hunt, Professor Emeritus at the University of California School of Medicine, has published important papers on many aspects of wound healing and is best known for his work on the effects of oxygen on repair. In addition to his own research, he has trained many fine clinicians and researchers in our field. It is fitting that Dr. Laura Bolton in the Evidence Corner honors Dr. Hunt by devoting her section to papers on the effects o
Effects of a Hydrofiber Dressing on Inflammatory Cells in Rat Partial-Thickness Wounds
- 2/10/2004
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Disclosure: This study was financially supported by grants from the Dutch Burns Foundation and ConvaTec, Deeside, United Kingdom.
Introduction
Wound healing starts with an inflammatory phase mediated mainly by neutrophils and macrophages. While the neutrophils are mainly responsible for host defense and cleansing of the wound, macrophages provide cytokines and growth factors that activate keratinocytes, fibroblasts, and endothelial cells to close the defect.[1] In the past, many approaches and wound dressings have been developed to improve the healing process, especially for deeper wound
Scalp Reconstruction after Resection of Malignant Fibrous Histiocytoma Utilizing a Dermal Regeneration Template: A Case Report
- 2/10/2004
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Introduction
Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma of adults. It is an aggressive soft tissue malignancy that is most commonly found in skeletal muscles or retroperitoneum. Cutaneous cases of MFH have been reported and commonly originate in the dermis and invade surrounding tissues.[1] The principle treatment modality for MFH is surgical excision with wide tumor-free margins. Reconstruction of partial- or full-thickness scalp defects encompasses many different techniques including the use of split-thickness skin grafts (STSG), full-thickness skin grafts
A Comparative Histological Study of Skin Graft Take with Tie-Over Bolster Dressing Versus Negative Pressure Wound Therapy in a P
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Disclosure: This study was funded by Providence Hospital Research Department, Southfield, Michigan.
Negative pressure wound therapy (NPWT) (Vacuum-Assisted Closure®, V.A.C.®, Kinetic Concepts Inc., San Antonio, Texas) has been shown to accelerate wound healing.[1] This may be due to removal of interstitial fluids, which could increase oxygen and nutrient delivery to tissues, leading to increased vascularity and granulation tissue, decreased bacterial colonization, and removal of inhibitory factors from chronic wound edema. The favorable effect of NPWT as a bolster for skin grafts was demo
Product and Industry News February 2004
- 2/10/2004
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Study Finds New Antibiotic, Linezolid, Effective for Diabetic Foot Infections
A clinical trial involving 371 patients in eight countries shows that linezolid, a new antibiotic, is at least as effective as two older therapies for treating diabetic foot infections. The drug may be an important new agent for doctors treating infections that are increasingly caused by bacteria resistant to standard antibiotics, and that in severe cases may require amputation. The study, led by a Department of Veterans Affairs (VA) physician and conducted at 30 US and 15 European sites, appeared in the January 1
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