Volume 14 - Issue 3 - March, 2002
Commentary: New Therapeutic Approaches in Wound Healing
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This issue of Wounds contains reports that, at first, might look quite heterogenous in their subject matter and not related to one another. Upon closer scrutiny, however, an important running theme exists—one that, in our opinion, will be the focus of increasing investigative work in the next several years. Let us explain that theme by analyzing these reports.
There is little doubt that the concept of wound bed preparation has drastically altered the way we view chronic wounds. Before this concept became popular, we tended to think of chronic wounds as acute wounds gone wrong. As a resu
Wound Bed Preparation and the Role of Enzymes: A Case for Multiple Actions of Therapeutic Agents
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Introduction
Technological Advances in Wound Bed Measurements
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Introduction
Chronic wounds represent a major challenge for the caregiver. Over the last few years, an increasing number of new technologies have been shown to be beneficial in wound management. These new opportunities to accelerate the tissue repair process together with a better knowledge of the pathogenetic mechanisms of chronic wounds have led to a more targeted therapeutic control of the different wound healing phases. In order to obtain biochemical and mechanical information about the wound bed and the surrounding skin, different options of noninvasive and invasive measurements have
Temporal Analysis of Gene Expression by Microarray During Wound Healing
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Introduction
Fundamental to our understanding of wound-healing biology is a knowledge of the signals that trigger relatively sedentary cell lineages at the wound margin to proliferate, become invasive, and then synthesize new matrix in the wound gap.1 The growth factors are key players in providing the signals to initiate and coordinate this complex process.2–4 Topical applications of growth factors to different animal models have demonstrated their ability to accelerate wound healing,5–7 providing evidence to support their signaling roles in wound healing.
One
The Use of Becaplermin as a Surgical Alternative in Difficult-to-Manage Soft Tissue Defects: Case Studies
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Introduction
Successful evaluation and treatment of soft tissue injuries require a broad understanding of anatomy as well as familiarity with the wide spectrum of available treatment options. The mechanism of injury is important, as it helps to delineate the nature and extent of tissue loss and functional limitations. The primary goals of reconstructive surgery are restoration of form and function. Once a wound has been characterized with respect to size, location, and exposed vital structures, the reconstructive ladder—a method-based algorithm emphasizing the selection of an operative t
March Product News
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3M Launches New Skin Health Website
3M’s newest Website gives healthcare professionals a resource for the skin health continuum of care—from healthy skin maintenance to prevention for at risk skin, treatment of damaged skin, and care for IV sites and wounds.
Found at www.3M.com/skinhealth, the site offers easy access to skin health-related clinical conditions and clinical solutions, latex reimbursement information, clinical practice tips, and links to 3M products and other professional Websites of interest to clinicians. It’s also easy to find selected 3M healthcare products that may b
March Industry News
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Chronic Wound Care, Third Edition “Highly Recommended” by NADONA
The National Association of Directors of Nursing Administration (NADONA) recently reviewed Chronic Wound Care: A Clinical Source Book for Healthcare Professionals, Third Edition (CWC), and highly recommended it to DONs. NADONA’s review was published in the Vol. 10, No. 1, 2002, edition of its official newsletter, The Director. The review describes CWC as, “the most comprehensive text available to those involved in care of patients afflicted with skin and wound problems. An outstanding value, a must for the DON’s librar
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