Volume 18 - Issue 7 - July, 2006
Editorial Message
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July, 2006
Dear Readers,
In the Evidence Corner, Dr. Laura Bolton summarizes results from randomized, controlled trials addressing the effects of preoperative hair removal and also preoperative skin antiseptics on the development of surgical site infections (SSIs). The published systematic reviews on these topics conclude 1) that there is no significant effect of preoperative hair removal using depilatory creams or razors on SSIs compared to no hair removal and 2) preoperative bathing with 4% chlorhexidine solution has no significant effect on postoperative SSIs compar
July 2006
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Dear Readers: Infection prevention is currently included among standardized hospital, home care, and ambulatory outpatient clinic quality measures.1 Thus far, only 2 actions are required of hospitals to meet quality standards—administration of prophylactic antibiotics within 1 hour prior to the surgical incision and discontinuance within 24 hours after the end of surgery.2 Other decisions significantly affect wound infection rates. For example, in hospitalized burn patients, limiting invasive device use and strictly adhering to aseptic technique
July 2006
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3M Survey Provides Insight into Simplifying Wound Care Practices
3M Health Care (St. Paul, Minn) recently sponsored a survey of wound care clinicians. The survey, conducted by HMP Communications (Malvern, Pa), the publisher of ECPN, Ostomy Wound Management, and WOUNDS, showed that selecting the most cost-effective wound dressing and managing exudate are the biggest issues a clinician faces when treating a wound. The survey results offer insight into the most significant issues wound care providers face and ways to simplify the job of wound care for clinician
July 2006
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Advanced BioHealing Aquires Rights and Assets for Dermagraft® and TransCyte®
Advanced BioHealing, Inc. (ABH, New York, NY) announces the company has concluded the acquisition of the assets and rights to the advanced wound care products Dermagraft® and TransCyte® from Smith & Nephew (Largo, Fla). Both products have been approved for marketing in the United States and other countries. The transaction transfers to ABH the assets and rights relating to these products. Financial terms were not disclosed.
Dermagraft is
Protective and Damaging Aspects of Healing: A Review
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Trauma, caused by mechanical, surgical, biological, or chemical means, generates a wound and activates a complex cascade of closely synchronized molecular events that initiate and complete the healing process.1 Although normal healing may slightly differ from tissue to tissue, the overall process has a similar protective role throughout the body.2 The damaging effects of abnormal healing caused by reduced or excessive healing activity may either lead to healing failure; acute, chronic, or over healing; and fibroproliferative scarring. The adaptation of trauma-activated
A Phase III Study to Evaluate the Safety and Efficacy of Recombinant Human Epidermal Growth Factor (REGEN-D™ 150) in Healing Dia
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A skin ulcer occurs when an area of skin has broken down and the underlying tissue can be seen. Most skin ulcers occur on the lower legs or the feet. In a normal person, the skin ulcer heals quickly after the injury. However, in a person with diabetes, the healing process is impaired and takes more time even if the injury is minor.
About 1 in 6 people with diabetes develop a foot ulcer at some stage.1,2 Such foot ulcers do not heal easily, are difficult to treat, and are more prone for serious infection. This calls for better treatment methods that address the causative pr
Lack of Reliability of Clinical/Visual Assessment of Chronic Wound Infection: The Incidence of Biopsy-Proven Infection in Venous
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For centuries, physicians have diagnosed skin and soft tissue infection using the classic signs and symptoms of erythema (rubor), warmth (calor), tenderness, purulent drainage, pain (dolor), and swelling (tumor). For the most part, these findings are reliable indicators of infection in the majority of acute and post-surgical wounds. However, Robson and Heggers1 demonstrated that surgeons evaluating wounds preoperatively by visual inspection prior to flap closure were unable to reliably determine which wounds were infected. The wounds with ≥ 106 colony-forming units
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