Volume 20 - Issue 2 - February, 2008

Duration of Disease, Neuropathic Symptoms, and Plantar Sensitivity in Patients With Diabetes With and Without Previous Plantar U

Disclosure: This project was supported by FAPESP Grant 2004/09585-2

The loss of protective sensation due to the consequences of the diabetic peripheral neuropathy (DPN) is one major risk factor for ulceration in diabetic feet.1–5 The prevalence of DPN is highly correlated to the duration of the diabetes, aging, and metabolic control.6 Approximately 20% of patients with diabetes will develop clinically significant DPN within 10 years of onset,7 and this frequency can increase to 50% after 10 or 15 years.8<



Placenta Derived Adherent Cell (PDAC) Interaction and Response on Extracellular Matrix Isolated from Human Placenta

The placenta is a rich source for proteins such as albumin,1 growth factors,2,3 and extracellular matrix proteins such as collagen4 and stem cells.5 This article describes the methods for the isolation of the whole placenta-derived extracellular matrix (pECM) tissue from the human placenta. The composition of the isolated matrix can be modified with slight changes in isolation methods.As the pECM is insoluble in water, this pECM material can be molded into water and cell culture media stable sheets and 3-dimensional (3-D) structures. Further, pEC



Use of Negative Pressure Wound Therapy in the Management of Wound Dehiscence in a Pregnant Patient

Case Report

A 28-year-old pregnant woman at 25 weeks gestation was transferred to the authors’ institution with abdominal pain caused by high-grade small bowel obstruction refractory to conservative treatment.The patient had an uncomplicated vaginal delivery 2 years earlier and an open appendectomy 6 months earlier. A decision was made to perform laparotomy due to the extent of obstipation and severity of abdominal tenderness.The patient was given ampicillin/sulbactam preoperatively.

An adhesive band was identified and divided through an upper mi



Limited Access Dressing

After 1960, apart from conventional closed dressing techniques, moist wound dressings and negative pressure dressings are the most commonly discussed in the literature.

The author designed the Limited Access Dressing (LAD) in an attempt to combine the advantages of both moist wound healing and negative pressure dressings.The design has notable advantages, while avoiding some major disadvantages such as an inaccessible, offensive smelling wound environment, and relatively high treatment costs.

Moist Wound Healing

It has been claimed that occ



Avoiding Shortcuts in Wound Care

Dear Readers,

Historically, the apothecary was the professional charged with making perfume. He would mix the best, most fragrant spices and resins to assure the most outstanding fragrance possible. His instruments of choice for producing the sweet smelling products were the mortar and pestle. As he stood at his workbench the sweet smell of the mixture would permeate the shop. Since there were no windows or window screens, flies and gnats were soon swarming around the mortar. Occasionally one of the winged visitors would get too close to the mixture and become trapped. The apothec



Letters to the Editor

Dear Editor:

This is in reference to the article: Leijnen M, et al. A Nonhealing Sinus of the Lower Leg 5 Years After Vacuum-assisted Closure Therapy Due To a Gossypiboma. WOUNDS. 2007;19(8):227–230. It should be noted by anyone using the KCI Wound V.A.C.® that KCI does not recommend placing black foam (GranuFoam) in deep openings, undermined areas, blind areas, or tunnels. It is recommended that the white foam (Vers-Foam), which is dense and has a higher tensile strength, be used for these areas. Also, when cutting t



February 2008

Smith & Nephew to Launch New Negative Pressure Wound Therapy Systems

Smith & Nephew (Largo, Fla) will announce the North American launch of its new portable negative pressure wound therapy (NPWT) systems, EZCARE and V1STA at Caesar’s Palace in Las Vegas, Nevada from February 29, 2008 through March 1, 2008.

The EZCARE standard system and V1STA portable system have achieved clinical results at low pressure (£ 80 mmHg), ultimately allowing better patient comfort and compliance. A panel of experts



February 2008

Medela Healthcare Launches Wound Therapy Rental Program

Medela Healthcare Inc (McHenry, Ill) recently launched its Medela ValuFlex Institutional Rental Program.

This rental plan allows healthcare facilities to lease the company’s Invia Healing System. Invia is a negative pressure wound therapy system used to safely and effectively heal chronic and acute wounds. The system’s infection preventing dual mechanism includes antimicrobial properties and an advanced wound dressing kit that controls infection and pro