Volume 20 - Issue 5 - May, 2008
The Need for New Wound Care Products
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Dear Readers,
Spring is here for most of the country.The cold,bleak days of winter are changing to the bright days of spring with green trees, beautiful flowers, pollen, and wound care meetings.Yes, spring is when we turn our attention to getting our educational juices flowing.We are excited about learning the new information that will be presented at national and regional wound care meetings and seeing all of the new wound care products.What a glorious time, but will our vision be fulfilled? Will there really be new and exciting information presented or will the speakers just
Safety and Efficacy of Wound Cleansers
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Dear Readers:
The adage “Cleanliness is next to godliness” seems to apply to wounds as well as people. Wounds have been cleansed since recorded history to remove foreign or necrotic matter, reduce odor, or more recently, to reduce bacterial burden. The evidence on cleansing, irrigation, and wound disinfection has been ably reviewed elsewhere,1 with appropriate techniques and cleansers described. Yet, we rarely know if we are doing more harm than good when cleansing a wound. Is it wise to wash away or dilute natural growth factors
Young Investigators
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The development of an infected acute wound porcine model
D. Boone, MD; E. Braitman, MD; J. Afthinos, MD; C. Gendics, RN; E. Sordillo, MD, PhD; G. Todd, MD; J. Lantis, MD; St. Luke’s-Roosevelt Hospital Center, New York, NY
Introduction: To assess potential antimicrobial and pro-growth agents available for wound healing, we found it necessary to develop a medium size animal model for infected wounds. While there are many animal models for infection, most of them include a wound inhibiting therapy as an adjunct, which can alter
Use of Single or Double Local Muscle Flap Transfers for Coverage of Tibia Bone Exposure
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One challenge in wound care is to effectively manage soft-tissue defects in the lower extremities, which usually coexist with Gustilo type IIIB open tibial fractures and full-thickness necrotizing fasciitis.1 In an attempt to salvage these open complex leg lesions, appropriate soft-tissue reconstruction is typically required to reduce the risk of bone infection and to increase the survival of exposed vital structures, thereby preventing limb amputation.2–4 Since the late 1980s, numerous medical centers started successfully reconstructing the majority of traumati
Importance of Skin Perfusion Pressure in Treatment of Critical Limb Ischemia
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Foot ulcers or gangrene with associated peripheral arterial disease (PAD) are a challenge to treat. Amputation of the toes and metatarsal bones is better tolerated than more extensive amputation because patients who undergo the former can be rehabilitated easily and can return to a good quality of life. In addition, the bony structures of the foot may be remodeled in such a way to prevent further injury.1 The evaluation of blood flow in the lower extremities is crucial in managing foot ulcers or gangrene with PAD. The goal of achieving the lowest possible level of amputation and
Topical Captopril as a Novel Agent Against Hypertrophic Scar Formation in New Zealand White Rabbit Skin
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Disclosure: The authors would like to thank the Vice Chancellor for research at the Jahrom School of Medical Sciences, Jahrom, Iran for supporting this research. Contract no. P/M/526–26.2.85.
Collagen constitutes the majority of extracellular matrix in tissues such as bone, cartilage, and especially the skin, and plays a major role in the process of wound healing. Following cutaneous injury, fibroblasts migrate to the site of trauma and produce collagen fibers that will increase the tensile strength of the scar. Abnormal wound healing due to o
Chronic Wound Infection: Bacterial Colonization in the Dermal Pericolostomic Region
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The incidence of septic complications following colostomy surgery varies from 0.5% to 25%.1–6 Wound infections appear to be more common following emergency stoma surgery, increasing the occurrence of sepsis in contaminated cases compared to noncontaminated cases. This can be explained by the contamination of the surgical site, starting from contact of the skin tissue with bacterial flora present in the intestinal lumen, which is not noted during clean procedures or those in which the intestine is not manipulated.7
Methods
April 2008
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Co-author Disagrees With Statements Made in Honey Leg Ulcer Trial Press Release
Editor’s Note: The following is a response to an Industry News piece published in the February 2008 issue of WOUNDS.
Professor Peter Molan, PhD, co-author of the study titled, “Randomized clinical trial of honey-impregnated dressings for venous leg ulcers,” has released a statement refuting misleading impressions made in a press release concerning the trial. The study was of 368 patients with venous leg ulcers, randomly assigned to get either
April 2008
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MedEfficiency Launches Assurance Boot
MedEfficiency Inc (Westminster, Colo) released a new Assurance Boot designed for use with its TCC-EZ™ total contact cast system. The Assurance Boot features a combination locking top strap and a secured inside cast that facilitates compliance with a patient’s offloading treatment regimen.
The TCC-EZ System uses a patented fishnet mesh cast technology that constructs a 1-layer cast and is protected by an outer shell. The shell provides support and stability for the patient suffering with a d
An Unexpected Detrimental Effect on the Incidence of Heel Pressure Ulcers After Local 5% DMSO Cream Application: A Randomized, D
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Pressure ulcers (PU) continue to be an enormous healthcare problem that affects large segments of the patient population. A PU is an area of localized damage to the skin and underlying tissues caused by pressure, shear, or friction.1 Apart from relief of tissue loading there are no appropriate therapies for preventing PU.
The complete etiology of PU is not yet fully understood. However, some components of the injury are caused by ischemia followed by reperfusion.2 Ischemia-reperfusion (I-R) injury has been defined as the injury, at the cellular level, result
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