Volume 20 - Issue 6 - June, 2008

SAWC/WHS 2008 Recap

Dear Readers,

The 2008 Symposium on Advanced Wound Care and Wound Healing Society Meeting (SAWC/WHS) is now history. As I dragged my weary body onto the airplane for the long flight across the country, I reflected on what just happened. Sometime in the midst of running to meetings and sessions, giving talks, moderating sessions, viewing posters, and viewing the exhibits, there is little time to actually reflect on the experience and what application it will have in your practice. I hope that all in attendance learned something new and exciting that will help them provide better



Biology and Treatment of Diabetic Foot Ulcers

Almost 5 years have passed since the last WOUNDS section dedicated to the Biology and Treatment of Diabetic Foot Ulcers was published. One major change since then is the awareness that diabetes, especially type 2, is becoming pandemic and poses significant social and economic challenges even among highly developed societies. Diabetic foot problems are also on the rise and it is expected that these problems will become more widespread as the number of patients with diabetes increases and their life expectancy is prolonged.

Unfortunately, no major therapeutic breakthrou



Living Cells or Collagen Matrix: Which Is More Beneficial in the Treatment of Diabetic Foot Ulcers?

Ulceration occurs in 4%–10% of people with diabetes in the United States and leads to amputation in approximately 30% of patients with diabetes who are 40 years and older.1 Each foot ulcer is associated with direct costs that can frequently exceed $45,000.2 The American Diabetes Association estimates that more than one-half of all amputations can be prevented with proper patient therapy. Diabetic neuropathy leads to functional impairment of microcirculation and can result in foot tissue hypoxia and reduced healing capacity, even in the presence of adequate blood



Classification, Diagnosis, and Treatment of Diabetic Foot Ulcers

The diabetic foot is considered one of the most significant complications of diabetes, representing a major worldwide medical, social, and economic problem that greatly affects patient quality of life. The risk for a patient with diabetes to develop a foot ulcer is close to 25%1 leading frequently to disablement and leg amputation.2,3 It has been estimated that every 30 seconds a lower limb is amputated somewhere in the world because of diabetes.4

The link between the diabetic foot ulcers and leg amputations is indisputable, as diabetes is the cau



The Influence of Gender as a Risk Factor in Diabetic Foot Ulceration

Diabetic foot complications such as ulcerations are a major health problem, estimated to occur in up to 15% of patients with diabetes during their lifetime.1 If insufficiently treated, these ulcerations can lead to lower extremity amputations and even death.2,3 The total cost of diabetic foot complications in the United States has been projected to approach $4 billion annually, as extrapolated from the costs of ulcer care and amputations.4 Therefore, identification of risk factors for foot ulceration is useful in both screening and prevention of these compl



High Rates of Comorbid Conditions in Patients With Type 2 Diabetes and Foot Ulcers

Foot ulceration in patients with diabetes mellitus (DM) affects quality of life and creates a significant economic burden for both the patient and healthcare systems worldwide.1–3 The annual incidence of foot ulcers is 1%–4% while the prevalence is 5%–10% in patients with DM.1,4 The lifetime risk for foot ulcers development in patients with diabetes is nearly 15%,1 and frequently leads to disability and leg amputation.1,2 The link between foot ulcers and leg amputations is indisputable, as diabetes is the cause of almost 50% of all nontrau



Use of a Novel Hydrosurgery Device in Surgical Debridement of Difficult-to-heal Wounds

Wound management is a substantial clinical and economic issue. Difficult wounds significantly affect the socioeconomic costs, and the progressive increase in population lifespan further accounts for the impact on health care spending.1–3 Today, clinicians share with patients a legitimate demand to limit the consequences of prolonged and/or important morbidity due to complex wounds, whether they are chronic or acute. This raises a compelling need to optimize wound care and requires simple, rapid, and safe treatment for all wound types. Exploitation of the insights coming fr



May 2008

Organogenesis to Develop Regenerative Medicine Therapies for US Military

Organogenesis Inc (Canton, Mass) has joined a consortium lead by the Regenerative Medicine at Wake Forest University Baptist Medical Center (Winston-Salem, NC), which has been awarded $42.5 million over 5 years by the US Army Institute of Surgical Research ([ISR], Fort Sam, Houston, Tex) to co-lead one of the two academic groups that will form the Armed Forces Institute of Regenerative Medicine (AFIRM).

The first group will involve the Wake Forest Institute for Regenerative Medicine an



May 2008

CAPTION System May Accelerate Natural Healing Response

Smith & Nephew Inc’s (Memphis, Tenn) Orthopaedic Trauma & Clinical Therapies business announced the US launch of the CAPTION Disposable Platelet Concentration System. The CAPTION system simplifies and expedites the collection of platelet rich concentrate (PRC) and eliminates cross-contamination risks.

Surgical staff can use the system to concentrate the platelets from a sample of the patient’s blood. When the concentrated platelets are applied