Volume 20 - Issue 7 - July, 2008

The Role of a Silver Releasing Lipido-colloid Contact Layer in Venous Leg Ulcers Presenting Inflammatory Signs Suggesting Heavy

Disclosure: This study was funded by a grant from URGO Laboratories, France. Dr. Meaume and Dr. Lazareth have served as paid speakers for URGO Laboratories. Dr. Sauvadet and Dr. Bohbot are employees of URGO Laboratories.

Nearly all open wounds are contaminated by microorganisms, but this generally corresponds to a simple bacterial growth without leading to deleterious effects or compromising the progress of the healing process. If the probability of wound infection increases as the level of contamination does in acute wounds, it is more complex



Closing Arguments


Dear Readers:

Wound closure would seem to have a rich evidence base of randomized controlled trials (RCTs), but new questions are leading to surprising answers. The first publication reviewed in this Evidence Corner explores the relative risks and benefits of closing pilonidal cyst excisions compared to open or secondary intention healing and offers conclusions that leave practicing clinicians with a choice between faster healing or reduced recurrence. The second review explores the relative merits of closing traumatic lacerat



New Wound Care Products: Don't Believe the Hype

Dear Readers,
Have you tried the new “whatumacallit” that debrides wounds, removes all the bacteria, restores the circulation, and heals the wound in 2 weeks just by passing the instrument over the wound? It is the coolest, most fantastic device I have ever seen! You have got to get one of those! And besides, it is FDA approved.

How often in wound care have we heard similar words? The new device, the new product, the new cream or ointment—each is the newest, best, and the “must have” product if we are going to provide “state of the a



Mast Cell Morphometry and Densitometry in Experimental Skin Wounds Treated With a Gel Containing Adelmidrol: A Placebo Controlle

Disclosure: This work was supported by the Royal Veterinary College (London, UK) research funds and by Innovet Italia Srl (Milan, Italy). The study was conducted at the Department of Animal Pathology, University of Pisa (Pisa, Italy). Alda Miolo is employed by Innovet Italia Srl and is in charge of the Documentation and Information Centre for the company.

Wound healing is a highly complex biological process that results from the interplay of different tissue structures and large numbers of infiltrating and resident cells.1,2 Among these,



Prevention of Projectile and Aerosol Contamination During Pulsatile Lavage Irrigation Using a Wound Irrigation Bag

Pulsatile lavage is a high-pressure wound irrigation system commonly used in operating rooms and wound care facilities. The system consists of a battery-powered device which delivers a pressurized sterile crystalloid solution to the wound bed at usually no greater than 15 psi. The device administers a fluid stream to the wound surface and has a built-in suction tube that concurrently removes the fluid as it is dispensed. A small circular shield is attached to the nozzle of the device, which serves to decrease gross splash when placed in contact with the wound bed. Tubing connects the devic



Assessment of a Wound Cleansing Solution in the Treatment of Problem Wounds

Problem wounds are rarely affected by a single factor.1 Delay in closure of a wound can result from problems such as poor perfusion, infection, pressure, and chronic venous hypertension.

To support wound healing, systemic factors and local factors should be addressed.1–4 Local barriers to healing must be removed before attempting wound closure.

Sometimes a wound may present as healthy and granulating and yet does not heal. This could be due to the wound bed containing nonviable (senescent) cells or cells of the wrong phenotype. In either cas



The Japanese Pressure Ulcer Surveillance Study: A Retrospective Cohort Study To Determine Prevalence of Pressure Ulcers in Japan

The increasing population of elderly people with high medical treatment costs throughout Japan is leading to an escalating financial burden.1 Pressure ulcers (PUs) are one of the most striking conditions affecting medical costs and quality of life among patients, specifically bed-ridden patients.2 In October 2002 a new governmental regulation system related to management of pressure ulcers was introduced in Japan. The Japan Ministry of Health, Labour, and Welfare implemented this regulation in all hospitals covered by the National Medical Insurance system. The regulat



June 2008

Versiva® XC Gelling Foam Dressings Manage Exudate and Minimize Pain

Versiva® XC (ConvaTec, Princeton, NJ) Gelling Foam Dressings with Hydrofiber® are now available in both adhesive and nonadhesive formulations for treating acute and chronic wounds.

Two recently published Phase II studies concerning leg and pressure ulcer management have shown the dressings to be effective in promoting wound healing by managing exudates, protecting the surrounding skin, and minimizing patient discomf



June 2008

Bristol-Myers Squibb Sells ConvaTec Business Unit

Bristol-Myers Squibb Company (New York, NY) has signed an agreement to sell its ConvaTec (Princeton, NJ) business unit to Nordic Capital Fund VII (Stockholm, Copenhagen, and Helsinki) and Avista Capital Partners (New York, NY and Houston, Tex) for $4.1 billion.

The transaction is subject to customary regulatory approvals and delivery of the company’s audited 2007 financial statements. The closing is anticipated to take place the third quarter of 2008.

The purchasers have entered into a fully



Veterinary Wounds


Veterinary Wounds

Mast cells (MCs) are found in many tissues and contain granules rich in histamine and heparin and a battery of mediators with proinflammatory and immunoregulatory potential. Although best known for their role in anaphylaxis and allergy, MCs also have an important protective role, as they are intimately involved in wound healing and defence against invasive pathogens.1,2 They are thought to originate from bone marrow precursors expressing the CD34 molecule and circulate in an immature form until they reach a tissue site whe



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