Volume 21 - Issue 3 - March, 2009

Pre-clinical Evaluation of a New Antimicrobial Enzyme for the Control of Wound Bioburden

Abstract: A new, optimized, antimicrobial enzyme system was developed for the control of wound bioburden. This Glucose oxidase-Lactoperoxidase-Guaiacol (GLG) system was analyzed for antimicrobial activity and cytotoxicity. The susceptibility of a wide range of antibiotic-resistant bacterial strains to the GLG-enzyme system was analyzed using minimum inhibitory concentration (MIC90), minimum bactericidal concentration (MBC) determination, and growth kinetics analysis. Additionally, challenge tests and cytotoxicity tests were performed with a new hydroactive alginate gel dressing with ant



Diagnosis and Treatment of Type II Necrotizing Fasciitis in a Child Presenting With Minor Abrasion, Edema, and Apparent Bruising

Abstract: A healthy, 14-year-old girl presented with what was initially a minor hand abrasion with edema and apparent ecchymosis. Over the next 12 hours, dusky rings developed over the forearm. Key features leading to diagnosis were pain out of proportion to the injury and a CT scan that was positive for gas in the tissues. Optimal limb salvage was obtained with an integrated, multidisciplinary approach that included hyperbaric medicine, surgery, infectious disease, wound care, rehabilitation services, and behavioral health. Multiple surgeries included debridement, layered matrix dressi



A Skin Chamber To Investigate Wound Infection and Healing in the Mouse

Abstract: The development of a simple, convenient, and reliable polypropylene screw-capped skin chamber, which can be inserted into mice, is described. All implanted chambers of normal immuno-competent mice (n = 10), or immuno-suppressed mice (n = 10) remained in-situ for 15 days. Wound infection was established by a clinical isolate of Pseudomonas aeruginosa in immuno-competent mice (n = 10) 1 day after chamber implantation and chambers remained in-situ for 10 days. Similar infections of wounds among mice immuno-suppressed with cyclophosphamide resulted in the mouse becoming moribund d



Time-related Concordance Between Swab and Biopsy Samples in the Microbiological Assessment of Burn Wounds

Abstract: The aim of this study was to investigate the concordance between swab and tissue biopsy samples in terms of microbiological isolates and their time-related changes. A total of 156 samples (78 swab and 78 biopsy) were collected from 39 cases of partial- or full-thickness burns and compared at days 7 and 14 after admission regarding the type of microorganisms and their time-related changes. Pseudomonas aeruginosa and Citrobacter freundii were the two most common microorganisms found by both sampling methods. While the majority of swab and biopsy samples were concordant in day 7,



Health Care Responsibilities in Tough Economic Times

Dear Readers,

     The economy is terrible. People are losing their jobs and homes. The hospital is so deep in debt it may close. What else could happen? In these troubled times it is easy to be overwhelmed by what is happening. Ann Landers, the late newspaper columnist, said, “When life’s problems seem overwhelming, look around and see what other people are coping with. You may consider yourself fortunate.” That is great advice for us since most of us are, indeed, fortunate even in such difficult times. But what about the people who are overwhelmed? Who will speak up t



SAWC Exhibitor Preview

April 26–29, 2009
Gaylord Texan Resort
Dallas, Texas
www.sawc.net

The following Exhibitor Preview highlights some of the companies, products, and services that will be showcased during the upcoming Symposium on Advanced Wound Care and Wound Healing Society Meeting (SAWC/WHS). Each exhibitor represents a valuable resource for learning, and provides an enjoyable way to meet the professionals who bring these products and services to you. Be sure to take the opportunity to see what they have in store for you in the SAWC/WHS 2



SAWC Oral Abstracts Preview

April 26–29, 2009
Gaylord Texan Resort
Dallas, Texas
www.sawc.net

More than 380 abstracts were submitted for presentation at the 2009 SAWC/WHS. Of those, 24 were accepted for oral presentation. The following is a preview of a few abstracts that will be presented during sessions 29–31, and sessions 42–44. The accepted poster presentations may be viewed throughout the entire meeting and during the scheduled poster session, which will be held Monday April 27 from 7:30am–9:30am. The 2nd annual Poster Gala and Awards will



Wound Infection: From the Bench to Bedside and Back

     Bacteria and other infectious organisms play a varied role in wound healing. Complicating acute wound healing by prolonging the inflammatory phase of healing, infectious organisms may cause a variety of wounds from epidermal loss associated with impetigo (Staphylococcus) and cold sores (herpes simplex), as well as deeper wounds causing ecthyma (Pseudomonas) or necrotizing fasciitis (aerobic or anaerobic bacteria).1–5 In some cases of non life-threatening infections, the host response to the infection, rather than the infectious organism itself, is primarily res



March 2009

The Continuum of Care Coalition Champions for Medicare and Medicaid Beneficiaries

     The Continuum of Care Coalition (C-3), a non-profit corporation, recently assumed the mantel as champions for Medicare and Medicaid Beneficiaries. C-3 has added the goal of deconsolidation of wound care from Consolidated Billing/Prospective Payment Programs to its agenda. The effort was started by American Medical Technologies (Irvine, Calif) in 2004. The program has the potential to reduce national health care costs by more than $2.2 billion annually and to improve the quality of ca



March 2009

Derma Sciences Gains FDA Clearance for BIOGUARD™ Barrier Dressing With NIMBUS® Technology

     Derma Sciences Inc (Princeton, NJ) announced that its first BIOGUARD™ Barrier Dressings have received US Food and Drug Administration (FDA) clearance for marketing and distribution. The dressing will offer surgeons, wound care clinicians, infection control experts, and primary care doctors a new weapon against the transmission of virulent bacteria, such as Methicillin-resistant Staphylococcus aureus (MRSA). With surgical site infections being such a serious concern in a



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