Dear Readers:

To honor T. K. Hunt, MD, Emeritus Professor of Surgery at the University of California, San Francisco, we devote this Evidence Corner to hyperbaric oxygen (HBO). Professor Hunt has been a mentor to many and a key contributor to the science of wound healing. Among his distinguished works, he and his colleagues discovered how chronic tissue hypoxia stimulates capillary proliferation.[1] As a result of this work, some hypothesized that increasing oxygen gradients by increasing the oxygen supply to tissue surrounding chronic wounds would improve healing, particularly for ischemic

February 2004

Dear Readers:

Last December, a symposium was held in San Francisco to honor Dr. Thomas K. Hunt for his contributions in wound healing research. Dr. Hunt, Professor Emeritus at the University of California School of Medicine, has published important papers on many aspects of wound healing and is best known for his work on the effects of oxygen on repair. In addition to his own research, he has trained many fine clinicians and researchers in our field. It is fitting that Dr. Laura Bolton in the Evidence Corner honors Dr. Hunt by devoting her section to papers on the effects o

Introduction

Malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma of adults. It is an aggressive soft tissue malignancy that is most commonly found in skeletal muscles or retroperitoneum. Cutaneous cases of MFH have been reported and commonly originate in the dermis and invade surrounding tissues.[1] The principle treatment modality for MFH is surgical excision with wide tumor-free margins. Reconstruction of partial- or full-thickness scalp defects encompasses many different techniques including the use of split-thickness skin grafts (STSG), full-thickness skin grafts

Study Finds New Antibiotic, Linezolid, Effective for Diabetic Foot Infections

A clinical trial involving 371 patients in eight countries shows that linezolid, a new antibiotic, is at least as effective as two older therapies for treating diabetic foot infections. The drug may be an important new agent for doctors treating infections that are increasingly caused by bacteria resistant to standard antibiotics, and that in severe cases may require amputation. The study, led by a Department of Veterans Affairs (VA) physician and conducted at 30 US and 15 European sites, appeared in the January 1