(continued from the June Editorial Message)

Poor perfusion and chronic tissue ischemia are common clinical scenarios particularly among older patients. Inciting pathologies ranging from peripheral vascular disease, venous congestion, and diabetes result in a compromised tissue bed with poor wound healing capacity, greater susceptibility to ulceration, and increased rates of infection. Efforts to better understand this ischemic condition have long employed the use of surgical flaps in the rat.

Disclosure: Joan Enric Torra i Bou, Lorena San Miguel, and John Posnett are paid employees of Smith & Nephew.

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