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Wound healing occurs in 3 overlapping phases: the inflammatory phase (“lag phase”), the proliferative phase (tissue formation), and the remodeling phase. In the proliferative phase, aside from angiogenesis, granulation tissue is formed and the wound is re-epithelialized.¹ In the authors’ wound clinic, re-epithelialization after successful debridement and granulation is sometimes the most difficult part of the wound closureprocess. Sometimes the wounds are very large and are preferably closed by split-thickness skin grafting.

More than 1000 different occlusive dressings are commercially available.¹ Occlusion may enhance wound healing primarily through the prevention of wound desiccation.As a result, epidermal necrosis and eschar formation do not occur, and wounds reepithelialize more rapidly.^2–7 However, the benefits of occlusive wound dressings remain sub judice for some.^8–15 Some animal studies indicate that fully occlusive dressings may suppress barrier recovery and reduce the epidermal proliferative response to an abnormal stratum corneum barrier.^8–11

AutoloGel^™ Platelet Rich Plasma Receives Marketing Clearance

Dear Readers,