Abstract: Treatment of necrotizing fasciitis (NF) includes radical surgical debridement often resulting in large wounds that need to be closed with methods including split-thickness skin grafts (STSG), local flaps, or guided tissue regeneration procedures. In this case report, a 45 year-old Caucasian male was surgically treated for a benign left groin hernia, developed NF, and was transferred to the authors’ burn unit. The wound was treated initially with wide debridement and with a brief delay before finally closing the wound.

Abstract: Background. Discoidin domain receptors (DDR) with tyrosine kinase activity have been identified as novel receptors for modulating collagen production and organization in scar tissue. The purpose of this study was to explore the effect of blocking discoidin domain receptor 1 (DDR1), signaling of keloid fibroblast cells on the inhibition of keloid formation, and proliferation, by means of gene therapy. Methods. The expression of DDR1 in keloid tissues was investigated by immunohistology and the expression of DDR1 protein in keloid fibroblasts was examined by Western blot analysis.

Dear Editor:

     I recently noticed an oversight in the article (Lountzis et al. Percutaneous flexor tenotomy—office procedure for diabetic toe ulcerations. WOUNDS. 2007;19[3]:64–68), which does not contain results on follow-up. The authors stated the procedure was “never described in an instructive fashion in the literature.” This author had previously published the technique and results on follow-up of this procedure in Wounds and elsewhere.^1–3 The editor, authors, and readers may find the excellent results on follow-up of interest.

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