Breaking the Barrier: An Innovative Approach to Mature Biofilm
Click HERE to view.
Addressing skin and wound bioburden is of utmost importance to wound care clinicians. The tendency of microorganisms to develop biofilms within a wound has been well documented in the literature. A recent meta-analysis underscored the presence of biofilm in 78.2% of chronic wounds. Biofilms may lead to chronic infection and impact wound healing by perpetuation of the inflammatory phase. Contrasting with free-floating, acutely infectious planktonic microorganisms, a biofilm is an aggregated colony of bacteria, usually of multiple species, that produces a protective EPS and establishes its own microenvironment that is conducive to survival. The biofilm and its surrounding EPS mature over time, and the more mature an EPS, the less susceptible it is to treatment modalities such as antibiotic or antimicrobial therapies. Although these mechanisms of biofilm formation, growth, and antimicrobial resistance have been investigated by the scientific community, there is still a need for effective treatments that address planktonic, immature, and mature biofilm-associated organisms in wound management.
Challenges for the bedside wound care provider in addressing biofilm include lack of diagnostic tools, availability of debridement modalities, and selection of evidence-based products that address planktonic microbes through mature biofilms while staying within a non-cytotoxic and cost-effective plan of care.
Treatment recommendations have shown that sharp debridement and topical antimicrobial applications can be used to address biofilm in wounds. Unfortunately, up to 30% of biofilm-infected wounds continued unresolved after sharp debridement, and therefore other options for mitigation of biofilm between debridement and dressing changes should be considered. These include good skin and wound cleansing and application of an effective antimicrobial dressing.
This presentation will discuss the challenges to addressing biofilm by the bedside clinician, present research findings related to topical antimicrobial agent effectiveness against planktonic, immature and mature biofilm, and tips for practical application techniques when addressing biofilm and mitigating its reformation. It will include case presentations of patients with wounds complicated by biofilm formation and using an effective treatment protocol.
Susan Dieter, MS, RN, CWS
Michael A. Maier, DPM
Rebecca McMahon, MBA, PhD
This webinar program is sponsored by:
By registering for this program, you consent to share the registration information with the program's sponsor(s).